The Baltimore Ravens are not just slight road favorites in Week 1 — they’re my best bet to kick off the 2025 NFL season.
Baltimore enters with one of the most complete rosters in the league and is fresh off an offseason where they addressed depth across the board. Lamar Jackson is coming off an MVP year, and he’s set up to attack a Bills defense missing key starters — including DT DeWayne Carter and potentially CB Tre’Davious White.
On the other side, Buffalo’s offensive line has questions, and they’ll be tested early by Baltimore’s aggressive front and disguised pressures. If the Ravens get out to an early lead, they can lean on clock control and a top-10 secondary to shut the door.
Factor in Baltimore’s 7–2 ATS record in Week 1 over the last nine years, and the edge is clear.
Best Bet: Ravens -1 — experience, health, and versatility give them the upper hand in Buffalo.